Top Summary: Shorter sleep duration can increase the risk of children developing depression, anxiety, and cognitive problems. Children who routinely suffered sleep disruptions or shorter sleep durations had reduced brain volume in the orbitofrontal cortex, prefrontal cortex, precuneus, supramarginal gyrus, and temporal

This review focuses on possible contributions of neural dedifferentiation to age-related cognitive decline. Neural dedifferentiation is held to reflect a breakdown in the functional specificity of brain regions and networks that compromises the fidelity of neural representations supporting episodic memory and related cognitive functions.

  A study published in the journal Neuroimage: Clinical found that patients with Major Depressive Disorder (MDD), who had recovered from symptoms, were able to strengthen some of their brain connections whilst thinking about guilt-evoking memories, thereby increasing their self-esteem.